Biyografi

   Postdoctoral Research Fellow, School of Medicine, Harvard University, 2020

   Postdoctoral Research Fellow, School of Medicine, Stanford University, 2018

   Ph.D. Biobehavioral Health, The Pennsylvania State University, 2015

   B.S. Biology, Hacettepe University, 2009

Our Lab Page: https://kislallab-psy.metu.edu.tr/en

Araştırma Alanları

Neuroscience studies in animal models:

• The impact of maternal obesity on offspring neurodevelopment

• Conditioned learning and memory in laboratory mice

• Animal models of neurodegenerative diseases

Örnek Yayınları

İlhan, Ç. F., Urcelay, G. P., & Kışlal, S. (2023). Genetic and environmental influences on one‐trial conditioned context aversion in mice. Genes, Brain and Behavior, e12857.

İlhan, Ç. F., & Kışlal, S. (2023). Memory Impairing Effect of Propranolol on Consolidation and Reconsolidation for Various Learning Tasks. Archives of Neuropsychiatry, 60(3), 271–282.

İlhan, Ç. F., & Kışlal, S. (2023). Interventions on Fear Memory for the Prevention of Post-Traumatic Stress Disorder. AYNA Clinic Psychology Journal, 10(3), 396-412.

Ülke, E & Kışlal, S. (2023). Omega-3 Yağ Asitlerinin Obeziteye Bağlı Nörobiyolojik ve Davranışsal Değişiklikler Üzerindeki Rolü, Nesne Dergisi.

İlhan, Ç. F., & Kışlal, S. (2023). Anticipatory Nausea and Vomiting in C57BL/6J Inbred Mice. Turkish Psychological Articles, 26(51), 1-13.

Kislal, S., Jin, W., Maesner, C., & Edlow, A. G. (2021). Mismatch between obesogenic intrauterine environment and low‐fat postnatal diet may confer offspring metabolic advantage. Obesity Science & Practice, 7(4), 450-461.

Caesarine, A., Batorsky, R., Shook, L., Kislal, S., Bordt, E., Devlin, B., ... & Edlow, A. (2021). Single cell profiling of Hofbauer cells and fetal brain microglia reveals shared programs and functions. bioRxiv Available at SSRN 3985607.

De Guzman, R., Batorsky, R., Kislal, S., Brigida, S., Bilbo, S., Slonim, D. K., & Edlow, A. G. (2021). 4 Placental Hofbauer Cells As a Proxy Cell Type for Fetal Brain Microglia. American Journal of Obstetrics & Gynecology, 224(2), S2-S3.

Kislal, S., Shook, L. L., & Edlow, A. G. (2020). Perinatal exposure to maternal obesity: Lasting cardiometabolic impact on offspring. Prenatal Diagnosis, 40(9), 1109-1125.

Shook, L. L., Kislal, S., & Edlow, A. G. (2020). Fetal brain and placental programming in maternal obesity: A review of human and animal model studies. Prenatal Diagnosis, 40(9), 1126-1137.

Ravina, K., Briggs, D., Kislal, S., Nguyen, T., Warraich, Z., Defensor, E., Zarembinski., T, Shamloo, M. (2018). Intracerebral Delivery of Brain-Derived Neurotrophic Factor Using HyStem®-C Hydrogel Implants Improves Functional Recovery and Reduces Neuroinflammation in a Rat Model of Ischemic Stroke. International Journal of Molecular Sciences, 19(12), 3782.

Kislal, S., & Blizard, D. A. (2017). Acquisition and Retention of Conditioned Aversions to Context and Taste in Laboratory Mice. Learning & Behavior, 1-15.

Kislal, S., & Blizard, D. A. (2016). Conditioned Context Aversion Learning in the Laboratory Mouse. Learning & Behavior, 44(4), 309-319.

Ishii, A., Koide, T., Takahashi, A., Shiroishi, T., Hettinger, T. P., Frank, M. E., Savoy, L. D., Formaker, B. K., Yertutanol, S., Lionikas, A., & Blizard, D. A. (2011). B6-MSM Consomic Mouse Strains Reveal Multiple Loci for Genetic Variation in Sucrose Octaacetate Aversion. Behavior Genetics 41(5), 716-723.

Sunumlar

Korkmaz D & Kışlal S (2023). Neuropsychological Tests Used in Offspring Exposed to Maternal Obesity and A High Fat Diet. Presented at the 2. International Boğaziçi Scientific Studies Congress, Turkey.

Akgül C & Kışlal S (2023). The Influence of Female Gonadal Hormones on Conditioned Context Aversion Learning. Presented at the Ege 9th International Conference on Social Sciences, Turkey.

Akgül C & Kışlal S (2023). Sex Differences in Conditioned Context Aversion. Presented at the 2. International Çankaya Scientific Studies Congress, Turkey.

İlhan F, Ülke E & Kışlal S (2023). C-fos Expression in Key Brain Regions Related to Conditioned Learning. Presented at the 6. International Food, Agriculture and Veterinary Sciences Congress.

Balci A & Kışlal S (2023). Deney Planlamasının Önemi ve Temel Aşamaları. Presented at the 5. International Dicle Scientific Research and Innovation Congress, Turkey.

Kışlal S (2023). Orta Serebral Arter Oklüzyonu Çalışmalarında Kullanılan Davranış Testleri. Presented at the 9. Uluslararası Sosyal Bilimler Kongresi, Turkey.

İlhan F & Kışlal S (2023). Memory Impairing Effect of Propranolol on Consolidation and Reconsolidation of Various Learning Tasks in Animal Models. Presented at the 1.Bilsel Uluslararasi Truva Bilimsel Araştirmalar ve Inovasyon Kongresi, Turkey.

İlhan F., Ülke E., Urcelay G., & Kışlal S. (2022). C Fos Expression in the Hippocampus Following Conditioned Context Aversion Learning in Mice. Presented at the 20. National Neuroscience Conference, Acıbadem University, Istanbul, Turkey.

İlhan F., Ülke E., Urcelay G., & Kışlal S. (2022). Effect of systemic MK-801 administration on the consolidation of conditioned context aversion memory. Presented at the International Symposium on Brain and Cognitive Science, Koç University, Turkey.

İlhan F., Ülke E., Urcelay G., & Kışlal S. (2022). The β-adrenergic Receptor Antagonist Propranolol Attenuates the Establishment of Conditioned Context Aversion in Laboratory Mice. Presented at the FENS Conference, Paris, France.

İlhan F., Şahin S., Urcelay G., & Kışlal S. (2022). Sex-Specific Conditioned Context Aversion in Outbred Mice as a Model of Anticipatory Nausea in Humans. Presented at the FENS Conference, Paris, France.

İlhan F., Ülke E., Şahin S., Urcelay G., & Kışlal S. (2021). Conditioned Context Aversion Learning in Inbred Mice. Presented at the 4th East Mediterranean Congress of Laboratory Animal Science, Turkey.

Şahin S., İlhan F., Urcelay G., & Kışlal S. (2021). Effects of stimulus pre-exposure on conditioned context aversion in CD1 outbred and C57BL/6J inbred mice. Presented at the 19. National Neuroscience Conference, Turkey.

De Guzman RM, Brigida SM, Kislal S, Rahmayanti S, Gilbert EA, Acharya KD, Bilbo SD, Perlis RH, Edlow AG (2023). Ablation of pro-inflammatory MyD88 signaling in fetal brain microglia ameliorates maternal obesity-induced hippocampal learning deficits in a sex-specific manner. Presented at the National Human Genome Research Institute (NHGRI) Research Training and Career Development Annual Meeting, Salt Lake City, UT 2023.

Kislal S. (2021) Sex-specific effects of maternal diet-induced obesity on fetal brain development and offspring behavior. Presented at the Massachusetts General Hospital, Harvad Medical School, Boston, USA.

Kislal S., Bilbo S., Slonim D., Edlow A. (2020) Placental Hofbauer Cells Mirror Fetal Brain Microglial Programming in Maternal Obesity. Presented at the Society for Reproductive Investigation, Vancouver, Canada.

Kislal S., William, J., Maesner, C., & Edlow, A. (2020) Maternal Obesity is Associated with Sedentary Behavior, Increased Sleep Duration, and Heightened Obesity Risk in Female Offspring. Presented at the Society for Reproductive Investigation, Vancouver, Canada.

Kislal S., William, J., Maesner, C., & Edlow, A. (2020) Maternal Obesity-associated Reduction in Offspring Mesolimbic Dopamine Signaling Correlates with Sex-specific Overeating and Obesity Risk. Presented at the Society for Maternal Fetal Medicine, Grapevine, Texas, USA.

Kislal S., William, J., Maesner, C., & Edlow, A. (2020) Mismatch Between Obesogenic Intrauterine Environment and Low-Fat Postnatal Diet May Confer an Offspring Metabolic Advantage. Presented at the Society for Maternal Fetal Medicine, Grapevine, Texas, USA.

Briggs, D., Ravina, K., Kislal, S., Warraich, Z., Nguyen, T., Lam, R., Zarembinski, T., Shamloo, M. (2018). Intracerebral delivery of brain-derived neurotrophic factor using HyStem®-C hydrogel implants improves functional recovery and reduces neuroinflammation in a rat model of ischemic stroke. Presented at the Society for Neuroscience, Conference, San Diego, CA, USA.

Briggs, D., Ravina, K., Kislal, S., Lam, R., Xu, C., Shamloo, M. (2018) Chemogenetic modulation of noradrenergic tone in the pathogenesis of ischemic stroke. Presented at the Society for Neuroscience, Conference, San Diego, CA, USA.

Ravina, K., Warraich, Z., Kislal, S., & Shamloo, M. (2016) Role of β-adrenoreceptor Partial Agonist in Pathophysiology and Recovery of Ischemic Stroke. Presented at the Society for Neuroscience Conference, San Diego, CA, USA.

Yertutanol, S and Blizard, D. A (2012) Aversion to sucrose octaacetate by laboratory mice is controlled by a polygenic system. Presented at the Graduate Research Exhibition, Penn State, University Park, PA, USA.

Blizard, D. A., Ishii, A., Koide, T., Takahashi, A., Shiroishi, T., Hettinger, T. P., Frank, M. E., Savoy, L. D., Formaker, B. K., Yertutanol, S., & Lionikas, A. (2011) Aversion to Sucrose Octaacetate by Laboratory Mice is Controlled by a Polygenic System. Presented at the Thirty-third Annual Meeting of the Association for St.Pete Beach, Florida, USA.

Projeler

• Principal investigator, ADEP, Turkey. Project Title: Maternal obeziteye maruz kalmış yüksek yağlı diyet ile beslenen yavru farelerde Omega takviyesinin dopaminerjik sisteme ve davranışa etkilerinin araştırılması

• Principal investigator, TUBITAK (3501) Career Development Program, Turkey. Project Title: Impairing Effect of Behavioral and Pharmacological Interventions on Fear Memory After CS or US Reminder

• Principal investigator, TUBITAK (2232) International Fellowship for Outstanding Researchers, Turkey TUBITAK. Project Title: Impairing memory consolidation to prevent the development of anticipatory nausea

Kitap Bölümleri

Sezen Kışlal (2023) Sinirbilim Alanında Yaygın Olarak Kullanılan Teknikler ve Davranış Testleri. Editör Y. Arslan. Sosyal Bilimlerde Aktüel Araştırmalar: Etkiler Sonuçlar (5) (ss.71-77). İstanbul: Kalan Yayınları.

Sezen Kışlal (2023) Deney Hayvanlarıyla Yapılan Çalışmalarda Araştırma Süreci: Temalar ve İşleyiş Testleri. Editör Y. Arslan. Sosyal Bilimlerde Aktüel Araştırmalar: Etkiler Sonuçlar (4) (ss.101-105). İstanbul: Kalan Yayınları.

Güncel ve Eski Lisansüstü Öğrenciler

Ceren Akgül

Diva Korkmaz

Gönüllü Çalışmaları ve Sertifikalar

2020: Assisted in COVID-19 research bio-repository efforts for pregnant women and newborns during the coronavirus pandemic. Harvard, School of Medicine, USA

2022: Completed the LEAD2 Young Academic Leadership Development Blended Training Program

Ödülleri

Ford Endowment Award. The Pennsylvania State University, Biobehavioral Health, USA

Üyelikleri

• Federation of European Neuroscience Societies

• Society for Neuroscience

• Society for Maternal Fetal Medicine

Verilen Dersler

PSY 3205 Introduction to Behavioural Neuroscience

PSY 2201: Learning

PSY 374: Biological Psychology

PSY 380: Topics in Experimental Psychology: Brain and Behaviour

PSY 583: Drugs, Brain and Behavior

PSY 5204: Advanced Behavioural Neuroscience